Which Individuals Have The Greatest Fitness In An Area Where Malaria Is Common? (Solution)

When living in a malaria-prone environment, which persons have the best physical fitness levels? Individuals who are heterozygous for the alleles that cause normal and sickle cell anemia. When just one copy of the allele is present, alleles for other hereditary illnesses can also confer protection against malaria in the absence of the other allele.
Who is the most vulnerable population in terms of malaria risk?

  • In malaria-endemic locations (such as Africa south of the Sahara), the most vulnerable individuals include: young children, who have not yet gained partial tolerance to malaria
  • pregnant women
  • and those with compromised immune systems. Expectant mothers, whose immune is weakened by pregnancy, particularly during the first and second pregnancies.


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Which individuals would be at a disadvantage in an area with high prevalence of malaria quizlet?

Persons who are homozygous for the sickle cell allele (who will develop sickle cell disease) and individuals who are homozygous for the normal hemoglobin allele (who can get malaria) both have a selection disadvantage in locations where the malaria parasite is present.

Which region has the highest percentage of individuals carrying a sickle cell allele?

millions of people worldwide are affected by sickle cell disease (SCD), which is particularly prevalent among those whose ancestors originated in sub-Saharan Africa, Spanish-speaking regions of the Western Hemisphere (South America, the Caribbean, and Central America), Saudi Arabia, India, and Mediterranean countries such as Greece and Italy.

When two alleles are maintained in a population because the heterozygote has higher fitness this is called?

The most likely reason is heterozygote superiority, which is also known as overdominance in some circles. According to this idea, heterozygotes have greater fitness than either homozygotes or either homozygotes.

What is the genotype that confers protection against malaria?

Even though the sickle hemoglobin (HbS) produced by a genetic mutation in the beta globin gene results in severe vascular complications that can lead to early death in individuals who are homozygous (SS) for that particular mutation, in its heterozygous form (AS), the mutation partially protects against severe malaria caused by Plasmodium falciparum.

What genotype is the most advantageous in areas where malaria is prevalent Why?

Infected individuals who have the AA genotype (who are homozygous for normal hemoglobin) are more vulnerable to malaria. Individuals with the AS genotype (heterozygous) are more resistant to malaria than those who do not have the genotype (homozygous). This is due in part to the fact that the malaria parasite is unable to replicate properly in these individuals.

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Which individuals have an advantage in an environment in which malaria is present?

Because they are protected from malaria in an environment where malaria is endemic, people who have the sickle cell allele have a selection advantage in environments where malaria is prevalent.

Who is most likely to have sickle cell anemia?

Who is at risk for sickle cell anemia? In the United States, the illness affects African Americans the most frequently (about 1 in every 400 African American births) and Hispanics of Caribbean heritage the second most frequently (1 in every 1,000 to 1,400 Hispanic American children).

Why is sickle cell more common in Africa?

The illness is most prevalent in sub-Saharan Africa, where up to 45 percent of the population is infected with the virus. It has spread so far because being a carrier provides a survival benefit against malaria, which is why it has become so ubiquitous. The Middle East does not have a significant malaria issue, and the general rate of sickle-cell carriers is low in the region.

Why is sickle cell only in African American?

The rationale for the high prevalence of sickle cell disease among black people is that possessing the trait (and hence only one copy of the mutant gene) renders persons more resistant to malaria than those who do not have the trait. Malaria is a major public health concern in Sub-Saharan Africa.

When heterozygotes have a higher fitness than homozygotes?

Heterozygote advantage is a type of balancing selection in which the heterozygote has a greater fitness than either of the homozygotes in question. Heterozygote advantage is referred to as overdominance for fitness in some circles. Sickle cell anemia in humans is perhaps the most well-known example of heterozygote advantage in nature.

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Which person has the highest evolutionary fitness?

Which individual possesses the highest level of evolutionary fitness? a guy who lives to be 68 years old and has seven children and fifteen grandkids; the ability to produce fruitful offspring is essential for evolutionary success.

What is the importance of heterozygotes in maintaining genetic variation?

What is the significance of heterozygotes, and specifically the heterozygote advantage, in the preservation of genetic variety in populations? Both alleles are present in the heterozygotes, which is required for genetic variety. Heterozygotes are required for the existence of genetic variety in a population to exist.

What genotype is the most beneficial for individuals living in regions where malaria is common?

A large number of African populations suffer from this condition. Patients with the sickle-cell allele (AS) are more resistant to malaria than the general population. As a result, they have a higher chance of surviving and reproducing. This ensures that the S allele remains in the gene pool.

How does sickle cell protect against malaria?

The sickle cells have membranes that become porous as a result of their unique form, allowing nutrients to seep out and allowing the parasites to thrive. The defective cells are ultimately destroyed by the organisms, which also destroys the parasite in the process.

Which 2 types of genetic hemoglobin disorders protect an individual in endemic areas from malaria?

2.3. 1 The number 2.3. 1 refers to the number 2.3. 1 of the UNIFORM UNIFORM UNIFORM UNIFORM UNIFORM Sickle hemoglobin (HbS), hemoglobin C (HbC), and Plasmodium falciparum malaria are all examples of hemoglobinopathies. Sickle hemoglobin (HbS) and hemoglobin C (HbC) are both hemoglobin variants that are generated by point mutations in the beta globin gene and both provide significant malaria resistance.

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